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pentobarbital will lower the level or impact of pioglitazone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.pentobarbital will decrease the level or impact of terbinafine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital will lower the level or outcome of glecaprevir